However, 12% of the invasive cancers diagnosed within six months with node staging had spread to the lymph nodes. About a third had ductal carcinoma in situ (DCIS), an early-stage, noninvasive form of breast cancer. Out of 43,628 women given BI-RADS 3 assessment after screening mammography recall, 810 (1.9%) were diagnosed with cancer. The women in the study group had no personal history of breast cancer and underwent either biopsy or two-year imaging follow-up. The study group included women recalled from screening mammography with BI-RADS 3 assessment at additional evaluation over a period of almost 10 years. Berg and colleagues assessed outcomes from six-, 12-, and 24-month follow-up of probably benign findings first identified on recall from screening mammography in the NMD. Berg, MD, PhD, a renowned breast cancer researcher at the University of Pittsburgh School of Medicine and professor of radiology at UPMC Magee-Womens Hospital in Pittsburgh.ĭr. ![]() “I thought that we should really look at this again now that we’ve got this large database we can work with and try to find out what happened with these patients,” said study lead author Wendie A. Study Showed that a Majority of Cancers Were Diagnosed Around Six-Month Follow-Up However, much of that research was done before the advent of the National Mammography Database (NMD). Some earlier research suggested that malignancies were so rare in the BI-RADS 3 group that follow-up could be safely pushed back from six months to a year. ![]() The interval for follow-up imaging has been a point of contention in the breast imaging community. This assessment means that the lesion is one of a few specific findings that has been shown to have less than a 2 percent chance of being cancer and that any cancer present is not likely to spread in the time frame recommended for follow-up imaging. Findings are classified based on the risk of breast cancer, with a BI-RADS 2 lesion being benign, or not cancerous, and BI-RADS 6 representing a lesion that is biopsy-proven to be malignant.īI-RADS 3, a probably benign finding, is a particularly challenging category that can cause confusion for physicians and anxiety for patients. The Breast Imaging and Reporting System (BI-RADS) was established by the American College of Radiology to help classify findings on mammography. ![]() Women with mammographically detected breast lesions that are probably benign should have follow-up surveillance imaging at six months due to the small but not insignificant risk that the lesions are malignant, according to a new study published in the journal Radiology.
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